Retinoblastoma (Phospho-Ser780) Rabbit mAb
This is a Retinoblastoma (Phospho-Ser780) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.
Synonyms
OSRC; RB; p105-Rb; pRb; RB1; pp110; Retinoblastoma 1; PPP1R130
Swiss Prot
P06400
Reactivity
Human
Immunogen
A synthesized peptide derived from human Retinoblastoma
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
110kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
EH5296 96 Tests
Human GPAA1 (Glycosylphosphatidylinositol anchor attachment 1 protein) ELISA Kit
Ask
View Details 
GTR15401382 1 Vial
Lentiviral human CRNKL1 sgRNA gene knockout kit - Lentiviral human CRNKL1 sgRNA gene knockout kit (25)
Ask
View Details MBS6131232-01 0.1 mL
FAM84A (Protein FAM84A, Neurologic Sensory Protein 1, NSE1, FLJ35392, PP11517) (AP)
Ask
View Details 
MBS6131232-02 5x 0.1 mL
FAM84A (Protein FAM84A, Neurologic Sensory Protein 1, NSE1, FLJ35392, PP11517) (AP)
Ask
View Details 276915-01 1 g
N-alpha-Fmoc-Nω- (4-toluenesulfonyl) -D-arginine (Fmoc-D-Arg (Tos) -OH)
Ask
View Details 
276915-02 5 g
N-alpha-Fmoc-Nω- (4-toluenesulfonyl) -D-arginine (Fmoc-D-Arg (Tos) -OH)
Ask
View Details