PP2A alpha (Phospho-Tyr307) Rabbit mAb
This is a PP2A alpha (Phospho-Tyr307) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
PP2A is the major phosphatase for microtubule-associated proteins (MAPs) . PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity) . Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Synonyms
Eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786
Swiss Prot
P67775
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Phospho-PP2A alpha (Y307)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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ATP6V1A, ID (ATP6V1A, ATP6A1, ATP6V1A1, VPP2, V-type proton ATPase catalytic subunit A, V-ATPase 69kD subunit, Vacuolar ATPase isoform VA68, Vacuolar proton pump subunit alpha)
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