YB1 (Phospho-Ser102) Antibody

This is a YB1 (Phospho-Ser102) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs) . Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A) n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.

Synonyms

CBF-A; NSEP1; EFI-A; MSY-1; YBX1

Gene ID

4904

Swiss Prot

P67809

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of Serine 102 (L-R-S (p) -V-G) derived from Human YB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.