Girdin (Phospho-Ser1417) Antibody
This is a Girdin (Phospho-Ser1417) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.
Synonyms
APE; GIV; GRDN; HkRP1; KIAA1212
Gene ID
55704
Swiss Prot
Q3V6T2
Reactivity
Human, Mouse
Immunogen
Peptide sequence around phosphorylation site of Serine 417 (Q-K-S (p) -L-T) derived from Human Girdin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Phospho-Specific Antibody
Applications
IHC
Purification Method
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Assay Type
Antibody
Concentration
1.0 mg/mL
Dilution
IHC 1:50-1:100
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Observed Molecular Weight
216kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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