MER/SKY (Phospho-Tyr749/681) Antibody

This is a MER/SKY (Phospho-Tyr749/681) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

Synonyms

C-mer; MERK; MERTK

Gene ID

10461

Swiss Prot

Q12866/Q06418

Reactivity

Human, Mouse

Immunogen

Peptide sequence around phosphorylation site of tyrosine 749/681 (K-I-Y (p) -S-G) derived from Human MER/SKY.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

WB, IHC

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.