Nuclear Receptor NR4A1 (Phospho-Ser351) Antibody
This is a Nuclear Receptor NR4A1 (Phospho-Ser351) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.
Synonyms
NGFIB; GFRP1; HMR; NR4A1; NAK1
Gene ID
3164
Swiss Prot
P22736
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of Serine351 (L-P-S (p) -K-P) derived from Human Nuclear Receptor NR4A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Phospho-Specific Antibody
Applications
IHC
Purification Method
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Assay Type
Antibody
Concentration
1.0 mg/mL
Dilution
IHC 1:50-1:100
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Observed Molecular Weight
64kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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