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Estrogen Receptor-ɑ (Phospho-Tyr537) Antibody

This is a Estrogen Receptor-ɑ (Phospho-Tyr537) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Synonyms

ER; ESR; ESR1; ESTR; NR3A1

Gene ID

2099

Swiss Prot

P03372

Reactivity

Human, Mouse

Immunogen

Peptide sequence around phosphorylation site of tyrosine 537 (P-L-Y (p) -D-L) derived from Human Estrogen Receptor-ɑ.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

WB, IHC

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.

Assay Type

Antibody

Concentration

1.0 mg/mL

Dilution

WB 1:500-1:1000, IHC 1:50-1:100

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Observed Molecular Weight

66kDa

Host or Source

Rabbit

Isotype

IgG

Curated Selection

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