P130 Cas (Phospho-Tyr410) Antibody
This is a p130 Cas (Phospho-Tyr410) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Synonyms
BCAR1; CRKAS; CRK-ASSOCIATED SUBSTRATE
Gene ID
9564
Swiss Prot
P56945
Reactivity
Human
Immunogen
Peptide sequence around phosphorylation site of tyrosine 410 (G-V-Y (p) -A-V) derived from Human p130 Cas.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Phospho-Specific Antibody
Applications
WB, IHC
Purification Method
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Assay Type
Antibody
Concentration
1.0 mg/mL
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Observed Molecular Weight
130kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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