FBXL3 (Phospho-Ser320) Antibody

This is a FBXL3 (Phospho-Ser320) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Substrate-recognition component of the SCF (FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF (FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF (FBXL3) complex is counteracted by the SCF (FBXL21) complex.

Synonyms

FBL3A; FBXL3A

Gene ID

26224

Swiss Prot

Q9UKT7

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 320 (S-V-S (p) -K-D) derived from Human FBXL3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.