IRS-1 (Phospho-Ser639) Antibody

This is a IRS-1 (Phospho-Ser639) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .

Synonyms

IRS-1; IRS1

Gene ID

3667

Swiss Prot

P35568

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 639 (P-K-S (p) -V-S) derived from Human IRS-1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

WB, IHC

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.