Zap-70 (Phospho-Tyr493) Antibody

This is a Zap-70 (Phospho-Tyr493) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not.

Synonyms

70 kDa zeta-associated protein; SRK; Syk-related tyrosine kinase; ZA70; ZAP-70

Gene ID

7535

Swiss Prot

P43403

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of tyrosine 493 (S-Y-Y (p) -T-A) derived from Human Zap-70.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

WB, IHC

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.