Tau (Phospho-Ser262) Antibody

This is a Tau (Phospho-Ser262) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Synonyms

MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau

Gene ID

4137

Swiss Prot

P10636

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 262 (I-G-S (p) -T-E) derived from Human Tau.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

WB, IHC, IF

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.