GSK3β (Phospho-Ser9) Antibody

This is a GSK3β (Phospho-Ser9) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin.

Synonyms

Factor A; GSK-3 beta; Protein kinase GSK-3-beta; kinase GSK-3 beta

Gene ID

2932

Swiss Prot

P49841

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 9 (T-T-S (p) -F-A) derived from Human GSK3β.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

WB, IHC, IF

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.