TORC1 Monoclonal Antibody
This is a TORC1 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.
Synonyms
KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1_HUMAN; FLJ14027; KIAA0616; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1
Gene ID
23373
Swiss Prot
Q6UUV9
Reactivity
Human, Mouse, Monkey, Rat
Immunogen
Purified recombinant human CRTC1 protein fragments expressed in E.coli.
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal
Applications
WB, ICC
Assay Type
Antibody
Dilution
WB 1:2000, ICC 1:200
Buffer
Ascites
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Observed Molecular Weight
78kDa
Host or Source
Mouse
Isotype
IgM
Curated Selection
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