GRB2 Monoclonal Antibody
This is a GRB2 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Synonyms
Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3
Gene ID
2885
Swiss Prot
P62993
Reactivity
Human, Rat, Mouse, Monkey
Immunogen
Purified recombinant human GRB2 protein fragments expressed in E.coli.
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal
Applications
WB
Assay Type
Antibody
Dilution
WB 1:500
Buffer
Ascites
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Observed Molecular Weight
25kDa
Host or Source
Mouse
Isotype
IgG1
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