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Histone H3 (mono methyl R2) Rabbit mAb

This is a Histone H3 (mono methyl R2) Rabbit mAb Methyl-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

Synonyms

Histone H3/a antibody Histone H3/b antibody Histone H3/c antibody Histone H3/d antibody Histone H3/f antibody Histone H3/h antibody Histone H3/i antibody Histone H3/j antibody Histone H3/k antibody Histone H3/l antibody

Gene ID

8.35083518352835e+39

Swiss Prot

P68431

Reactivity

Human, Mouse

Immunogen

Recombinant protein

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Methyl-Specific Antibody

Applications

WB, ICC/IF

Purification Method

ProA affinity purification

Assay Type

Antibody

Dilution

WB 1:1000, ICC 1:50-1:200

Buffer

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

15 kDa

Host or Source

Rabbit

Curated Selection

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