Histone H3 (mono methyl K36) Rabbit mAb
This is a Histone H3 (mono methyl K36) Rabbit mAb Methyl-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
In eukaryotes, DNA is wrapped around histone octamers to form the basic unit of chromatin structure. The octamer is composed of histones H2A, H2B, H3 and H4, and it associates with approximately 200 base pairs of DNA to form the nucleosome. The association of DNA with histones results in dense packing of chromatin, which restricts proteins involved in gene transcription from binding to DNA. Histone H3, the core protein of the nucleosome, becomes phosphorylated at the end of prophase. The two major sites of phosphorylation are the mitosis-specific site Ser10, and Ser28, both of which are extensively phosphorylated in DNA-bound forms of histone H3 and in nucleosomal histone H3. The nucleosome structure of histone H3 promotes N-terminal phosphorylation in vitro.
Synonyms
Histone H3/a antibody Histone H3/b antibody Histone H3/c antibody Histone H3/d antibody Histone H3/f antibody Histone H3/h antibody Histone H3/i antibody Histone H3/j antibody Histone H3/k antibody Histone H3/l antibody
Gene ID
8.35083518352835e+39
Swiss Prot
P68431
Reactivity
Human, Mouse
Immunogen
Recombinant protein
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Methyl-Specific Antibody
Applications
WB, ICC/IF
Purification Method
ProA affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:2000, ICC 1:50-1:200
Buffer
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa
Host or Source
Rabbit
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