Histone H4 (acetyl K5) Rabbit mAb
This is a Histone H4 (acetyl K5) Rabbit mAb Acetyl-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Synonyms
H4C1; H4/A; H4FA; HIST1H4A; H4C2; H4/I; H4FI; HIST1H4B; H4C3; H4/G; H4FG; HIST1H4C; H4C4; H4/B; H4FB; HIST1H4D; H4C5; H4/J; H4FJ; HIST1H4E
Gene ID
1.21504554313829e+59
Swiss Prot
P62805
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Acetyl-Specific Antibody
Applications
WB, ICC/IF, IHC, IP
Purification Method
ProA affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200, ICC 1:50-1:200
Buffer
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
11 kDa
Host or Source
Rabbit
Curated Selection
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