AF/LE Purified Anti-Mouse CD1d Antibody[1B1]

Product Specifications

Background

CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e) . But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.

Abbreviation

CD1d

Gene ID

12479

UniProt

P11609

Host

Rat

Reactivity

Mouse

Immunogen

Recombinant Mouse CD1d protein

Target

Antigen-presenting glycoprotein CD1d; Antigen-presenting glycoprotein CD1d1; CD1d.1; Cd1.1; Cd1d1; CD1; Ly-38; CD1.1; CD1.2; AI747460; Cd1a; Cd1d; Ly-38

Clonality

Monoclonal

Clone

1B1

Conjugation

None (AF/LE)

Applications

FCM

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.