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5-Aminolevulinic acid-15N (hydrochloride)

5-Aminolevulinic acid-15N (hydrochloride) is the 15N-labeled 5-Aminolevulinic acid (hydrochloride) . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

Product Specifications

CAS Number

116571-80-3

Product Name Alternative

5-ALA-15N (hydrochloride) ; δ-Aminolevulinic acid-15N (hydrochloride) ; 5-Amino-4-oxopentanoic acid-15N (hydrochloride)

UNSPSC

12352211

Target

Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Mitophagy

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/5-aminolevulinic-acid-15n-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CCC(C[15NH2])=O.[H]Cl

Molecular Formula

C5H10Cl 15NO3

Molecular Weight

168.58

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7 (5) : p. 392-401.|[3]Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7 (9) : p. e44885.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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