OX04528
Product Specifications
UNSPSC Description
OX04528 (compound 68) is a potent, G-protein biased, and orally active GPR84 agonist. OX04528 no cytotoxicity. OX04528 inhibits cAMP production with an EC50 value of 0.00598 nM[1].
Target Antigen
GPR84
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ox04528.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[O-][N+]1=CC(CCCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=CC(O)=C1
Molecular Weight
365.27
References & Citations
[1]Wang P, et al. Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists. J Med Chem. 2024 Jan 11;67(1):110-137.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161106/OX04528-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161106/OX04528-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3028055-45-7
Available Sizes
Curated Selection
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