Vinburnine
Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
Product Specifications
CAS Number
4880-88-0
Product Name Alternative
(-) -Eburnamonine; (-) -Vincamone
UNSPSC
12352005
Hazard Statement
H373
Target
Drug Metabolite; mAChR
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Vinburnine.html
Purity
99.78
Solubility
DMSO : 8.33 mg/mL (ultrasonic)
Smiles
O=C1C[C@@]2(CC)[C@@]3([H])C(N1C4=CC=CC=C54)=C5CCN3CCC2
Molecular Formula
C19H22N2O
Molecular Weight
294.40
Precautions
H373
References & Citations
[1]Maksay G, Bíró T, Kiss B. Vinburnine decelerates [3H]N-methylscopolamine binding to recombinant human muscarinic M1-M4 acetylcholine receptors. Eur J Pharmacol. 2004;483 (2-3) :229-232. |[2]Drago F, et al., Effects of vinburnine on experimental models of learning and memory impairments. Pharmacol Biochem Behav. 1990 Sep;37 (1) :53-7.|[3]Vas A, et al., Eburnamine derivatives and the brain. Med Res Rev. 2005 Nov;25 (6) :737-57.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
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