Bemotrizinol
Bemotrizinol (Tinosorb S), a compound that can absorb ultraviolet light, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation[1][2][3][4].
Product Specifications
CAS Number
187393-00-6
Product Name Alternative
Tinosorb S
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bemotrizinol.html
Purity
98.0
Solubility
Chloroform : 50 mg/mL (ultrasonic)
Smiles
CCCCC(CC)COC1=CC(=C(C=C1)C2=NC(=NC(=N2)C3=CC=C(C=C3)OC)C4=C(C=C(C=C4)OCC(CC)CCCC)O)O
Molecular Formula
C38H49N3O5
Molecular Weight
627.81
Precautions
H302, H315, H319, H335
References & Citations
[1]Durán-Giner N, et al. Solar filters as feasible acceptors of atomic oxygen. Photochem Photobiol Sci. 2013;12 (5) :725-728.|[2]D'Ruiz CD, et al. Preliminary clinical pharmacokinetic evaluation of bemotrizinol - A new sunscreen active ingredient being considered for inclusion under FDA's over-the-counter (OTC) sunscreen monograph. Regul Toxicol Pharmacol. 2023 Mar;139:105344.|[3]Hashim D M, et al. Enhancing the sunscreen efficacy of bemotrizinol micropigment by using o/w nanoemulsion topical preparations[J]. Int J Pharm Pharm Sci, 2019, 11 (7) : 47-56.|[4]Yap FH, et al. Active sunscreen ingredients in Australia. Australas J Dermatol. 2017 Nov;58 (4) :e160-e170.|[5]Sarpietro M G, et al. Bemotrizinol-Loaded Nanostructured Lipid Carriers for the Development of Sunscreen Emulsions[J]. Journal of Microencapsulation, 2024.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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