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FITC-Lithocholic acid 3-sulfate

FITC-Lithocholic acid 3-sulfate (FITC-Sulfolithocholic acid) is a FITC-labeled Lithocholic acid 3-sulfate, which is a sulfated biliary metabolite. Lithocholic acid 3-sulfate selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate can be used for the research of pathogenesis of cholestatic liver diseases[1].

Product Specifications

Product Name Alternative

FITC-Sulfolithocholic acid

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fitc-lithocholic-acid-3-sulfate.html

Purity

90.01

Solubility

10 mM in DMSO

Smiles

C[C@H](CCC(NCCNC(NC1=CC=C(C2=C(C=C3)C(OC4=C2C=CC(O)=C4)=CC3=O)C(C(O)=O)=C1)=S)=O)[C@H]5CC[C@@]6([H])[C@]7([H])CC[C@]8([H])C[C@H](OS(=O)(O)=O)CC[C@]8(C)[C@@]7([H])CC[C@]56C

Molecular Formula

C47H57N3O10S2

Molecular Weight

888.10

References & Citations

[1]Xiao R, et al. Synthesis and identification of lithocholic acid 3-sulfate as RORγt ligand to inhibit Th17 cell differentiation. J Leukoc Biol. 2022 Oct;112 (4) :835-843.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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