Mulberrin
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1) -mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.
Product Specifications
CAS Number
[62949-79-5]
Product Name Alternative
Kuwanon C
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
OAT
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Mulberrin.html
Concentration
10mM
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C/C(C)=C\CC1=C2C(C(C(C/C=C(C)\C)=C(C3=C(C=C(O)C=C3)O)O2)=O)=C(O)C=C1O
Molecular Formula
C25H26O6
Molecular Weight
422.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Wen F, et al. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol. 2016;54 (2) :293-302.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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