Fibrinogen-Binding Peptide

Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin[1].

Product Specifications

CAS Number

[137235-80-4]

UNSPSC

12352209

Target

Thrombin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fibrinogen-binding-peptide.html

Purity

99.83

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C[C@@H](C(O)=O)NC([C@H]1N(C([C@H]([C@@H](C)CC)NC([C@H](CC2=CNC=N2)NC([C@H](CCC(O)=O)N)=O)=O)=O)CCC1)=O

Molecular Formula

C25H39N7O8

Molecular Weight

565.62

References & Citations

[1]Gartner TK, et al. The peptide Glu-His-Ile-Pro-Ala binds fibrinogen and inhibits platelet aggregation and adhesion to fibrinogen and vitronectin. Proc Soc Exp Biol Med. 1991 Oct;198 (1) :649-55.