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1,2-Dihydropyridazine-3,6-dione-3,4,5,6-13C4

Selected Variant

HY-59354S1

Size: 1 Each

1,2-Dihydropyridazine-3,6-dione-3,4,5,6-13C4 (1,2-Dihydro-3,6-pyridazine-13C4-dione) is 13C labeled Maleic hydrazide. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[1][2].

Product Specifications

CAS Number

2140327-62-2

Product Name Alternative

1,2-Dihydro-3,6-pyridazine-13C4-dione; 3,6-Dihydroxypyridazine-13C4; 3,6-Pyridazine-13C4-diol; Maleic hydrazide-13C4

UNSPSC

12352005

Target

DNA/RNA Synthesis; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-2-dihydropyridazine-3-6-dione-3-4-5-6-13c4.html

Smiles

O=[13C]1[13CH]=[13CH][13C](NN1)=O

Molecular Formula

13C4H4N2O2

Molecular Weight

116.06

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16.|[3]Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 1978;55 (1) :15-30.|[4]Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 2014;37 (4) :459-465.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

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