Catenin δ-1 (phospho-Ser252) rabbit pAb

Catenin delta 1 (CTNND1) Homo sapiens This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010],

Product Specifications

Background

Product Name Alternative

Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120 (ctn) ) (p120 (cas) )

UniProt

O60716

Swiss Prot

O60716

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized phosho peptide around human Catenin δ-1 (Ser252)

Target

Catenin δ-1

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Buffer

-20°C/1 year

Molecular Weight

108kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

108kD

Fragment

IgG

Subcellular Location

Cell junction, adherens junction . Cytoplasm . Nucleus . Cell membrane . Interaction with GLIS2 promotes nuclear translocation (By similarity) . Detected at cell-cell contacts (PubMed:15240885, PubMed:17047063) . NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm (PubMed:17047063) . CDH1 enhances cell membrane localization (PubMed:15240885) . Isoforms 4A and 1AB are excluded from the nucleus (PubMed:11896187) . .; [Isoform 1A]: Nucleus .; [Isoform 2A]: Nucleus .; [Isoform 3A]: Nucleus .