PD-1/PD-L1-IN-50
PD-1/PD-L1-IN-50 (Compound LG-12) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-50 increases the secretion of IFN-γ to promote CD8 + T cell activation, and activates the antitumor immunity of T cells[1].
Product Specifications
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-50.html
Smiles
IC1=C(OCC2=CC=CC(C3=CC=C4C(OCCO4)=C3)=C2C)C=C(OCC5=CC=CC(C#N)=C5)C(NC(CO)(CO)CO)=C1
Molecular Formula
C34H33IN2O7
Molecular Weight
708.54
References & Citations
[1]Lv G, et al. Synthesis and immunotherapy efficacy of a PD-L1 small-molecule inhibitor combined with its 131I-iodide labelled isostructural compound. Bioorg Chem. 2024 Sep 7;153:107810.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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