Irinotecan (hydrochloride)
Irinotecan hydrochloride ((+) -Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer[1].
Product Specifications
CAS Number
[100286-90-6]
Product Name Alternative
(+) -Irinotecan (hydrochloride) ; CPT-11 (hydrochloride) ; VAL-413
UNSPSC
12352005
Hazard Statement
H302
Target
Autophagy; Topoisomerase
Type
Natural Products
Related Pathways
Autophagy; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Irinotecan-hydrochloride.html
Purity
99.89
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 3.33 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(N2CCCCC2)CC1)OC3=CC=C4N=C5C(CN6C(C(COC([C@@]7(CC)O)=O)=C7C=C65)=O)=C(CC)C4=C3.[H]Cl
Molecular Formula
C33H39ClN4O6
Molecular Weight
623.14
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Topo I
Citation 01
Available Sizes
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