Tachyplesin I
Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane[1].
Product Specifications
CAS Number
118231-04-2
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/tachyplesin-i.html
Purity
99.20
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N[C@@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](N1)CC(C=C2)=CC=C2O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@](CSSC[C@@](NC([C@](N3)([H])[C@@H](C)CC)=O)([H])C1=O)([H])C(N[C@H](C(N[C@H](C(NCC3=O)=O)CCCNC(N)=N)=O)CC(C=C4)=CC=C4O)=O)=O)C(C)C)=O)CCCNC(N)=N)=O)CC5=CC=CC=C5)=O)[C@@H](NC([C@@H](N)CCCCN)=O)CC6=CNC7=CC=CC=C67
Molecular Formula
C99H151N35O19S4
Molecular Weight
2263.74
References & Citations
[1]D V Kuzmin, et al. In Vitro Study of Antitumor Effect of Antimicrobial Peptide Tachyplesin I in Combination with Cisplatin. Bull Exp Biol Med. 2018 Jun;165 (2) :220-224.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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