Tachyplesin I

Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane[1].

Product Specifications

CAS Number

[118231-04-2]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/tachyplesin-i.html

Purity

99.20

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N[C@@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](N1)CC(C=C2)=CC=C2O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@](CSSC[C@@](NC([C@](N3)([H])[C@@H](C)CC)=O)([H])C1=O)([H])C(N[C@H](C(N[C@H](C(NCC3=O)=O)CCCNC(N)=N)=O)CC(C=C4)=CC=C4O)=O)=O)C(C)C)=O)CCCNC(N)=N)=O)CC5=CC=CC=C5)=O)[C@@H](NC([C@@H](N)CCCCN)=O)CC6=CNC7=CC=CC=C67

Molecular Formula

C99H151N35O19S4

Molecular Weight

2263.74

References & Citations

[1]D V Kuzmin, et al. In Vitro Study of Antitumor Effect of Antimicrobial Peptide Tachyplesin I in Combination with Cisplatin. Bull Exp Biol Med. 2018 Jun;165 (2) :220-224.