S-palm P0 (180–199) (TFA)

S-palm P0 (180–199) (TFA) is a peptide that enhances MHC II-restricted responses. S-palm P0 (180–199) (TFA) can be used to establish models of chronic inflammatory demyelinating polyneuropathy (CIDP) and chronic experimental autoimmune neuritis (c-EAN) . S-palm P0 (180–199) (TFA) is used for studying autoimmune-mediated neuroinflammatory diseases[1][2].

Product Specifications

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/s-palm-p0-180-199-tfa.html

Purity

97.46

Solubility

H2O : ≥ 50 mg/mL

Smiles

O=C(N[C@@H](CSC(CCCCCCCCCCCCCCC)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N.OC(C(F)(F)F)=O.[x]

Molecular Formula

C112H191N33O29S2.xC2HF3O2

Molecular Weight

2528.05 (free base)

References & Citations

[1]Feng Y, et al. Fingolimod ameliorates chronic experimental autoimmune neuritis by modulating inflammatory cytokines and Akt/mTOR/NF-κB signaling. Brain Behav. 2023 Apr;13 (4) :e2965.|[2]Brun S, et al. Assessing Autophagy in Sciatic Nerves of a Rat Model that Develops Inflammatory Autoimmune Peripheral Neuropathies. Cells. 2017 Sep 18;6 (3) :30.