Sandaracopimaric acid
Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].
Product Specifications
CAS Number
[471-74-9]
UNSPSC
12352211
Target
GABA Receptor
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sandaracopimaric-acid.html
Purity
98.86
Solubility
DMSO : 3.5 mg/mL (ultrasonic; warming)
Smiles
O=C([C@]1(C)CCC[C@]2(C)[C@@]3([H])CC[C@](C)(C=C)C=C3CC[C@@]12[H])O
Molecular Formula
C20H30O2
Molecular Weight
302.45
References & Citations
[1]Wenyan Gao, et al. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules. 2014 Jun 23;19 (6) :8503-17.|[2]Masao Takei, et al. Diterpenes drive Th1 polarization depending on IL-12. Int Immunopharmacol. 2008 Nov;8 (11) :1602-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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