Sandaracopimaric acid

Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].

Product Specifications

CAS Number

[471-74-9]

UNSPSC

12352211

Target

GABA Receptor

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sandaracopimaric-acid.html

Purity

98.86

Solubility

DMSO : 3.5 mg/mL (ultrasonic; warming)

Smiles

O=C([C@]1(C)CCC[C@]2(C)[C@@]3([H])CC[C@](C)(C=C)C=C3CC[C@@]12[H])O

Molecular Formula

C20H30O2

Molecular Weight

302.45

References & Citations

[1]Wenyan Gao, et al. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules. 2014 Jun 23;19 (6) :8503-17.|[2]Masao Takei, et al. Diterpenes drive Th1 polarization depending on IL-12. Int Immunopharmacol. 2008 Nov;8 (11) :1602-8.