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Sandaracopimaric acid

Product Specifications

UNSPSC Description

Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].

Target Antigen

GABA Receptor

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sandaracopimaric-acid.html

Purity

98.86

Solubility

DMSO : 3.5 mg/mL (ultrasonic;warming)

Smiles

O=C([C@]1(C)CCC[C@]2(C)[C@@]3([H])CC[C@](C)(C=C)C=C3CC[C@@]12[H])O

Molecular Weight

302.45

References & Citations

[1]Wenyan Gao, et al. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules. 2014 Jun 23;19(6):8503-17.|[2]Masao Takei, et al. Diterpenes drive Th1 polarization depending on IL-12. Int Immunopharmacol. 2008 Nov;8(11):1602-8.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-133594/Sandaracopimaric-acid-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-133594/Sandaracopimaric-acid-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

471-74-9

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