β-Aminopropionitrile (hydrochloride)
Product Specifications
UNSPSC Description
β-Aminopropionitrile (BAPN) hydrochloride is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile hydrochloride targets the active site of LOX or LOXL isoenzymes[1][2].
Target Antigen
Endogenous Metabolite; Monoamine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/β-aminopropionitrile-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
NCCC#N.Cl
Molecular Weight
106.55
References & Citations
[1]Miana M, et al. The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats. Dis Model Mech. 2015 Jun;8(6):543-51.|[2]Yang X, et al. Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep. 2013 Feb;29(2):541-8.|[3]Ren W, et al. β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice. Sci Rep. 2016 Jun 22;6:28149.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-Y1750A/β-Aminopropionitrile-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-Y1750A/
Clinical Information
No Development Reported
CAS Number
646-03-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
