Desoxycarbadox-d3

Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340) . Carbadox is a quinoxaline-di-N-oxide antibiotic compound.

Product Specifications

CAS Number

[1448350-02-4]

UNSPSC

12352005

Hazard Statement

H228-H302-H350

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.78

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C/C1=NC2=CC=CC=C2N=C1)OC([2H])([2H])[2H]

Molecular Formula

C11H7D3N4O2

Molecular Weight

233.24

Precautions

P210-P240-P241-P264-P270-P280-P330-P370+P378-P405-P501

References & Citations

[1]Looft T, et al. Carbadox has both temporary and lasting effects on the swine gut microbiota. Front Microbiol. 2014;5:276. Published 2014 Jun 10.|[2]MacIntosh AI, et al. Liquid chromatographic monitoring of the depletion of carbadox and its metabolite desoxycarbadox in swine tissues. J Assoc Off Anal Chem. 1985;68 (4) :665-671.|[3]Zhang K, et al. Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites. Environ Toxicol Pharmacol. 2015;39 (2) :555-567.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.