Amiprofos methyl

Amiprofos methyl (BAY-NTN 6867) is a phosphoric amide herbicide. Amiprofos methyl is a specific and potent antimicrotubule agent. Amiprofos methyl directly poisons microtubule dynamics in plant cells[1].

Product Specifications

CAS Number

[36001-88-4]

Product Name Alternative

BAY-NTN 6867

UNSPSC

12352005

Hazard Statement

H302

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/amiprofos-methyl.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

S=P(OC)(NC(C)C)OC1=CC=C(C)C=C1[N+]([O-])=O

Molecular Formula

C11H17N2O4PS

Molecular Weight

304.30

Precautions

H302

References & Citations

[1]Morejohn LC, et al. Inhibition of Plant Microtubule Polymerization in vitro by the Phosphoric Amide Herbicide Amiprophos-Methyl. Science. 1984;224 (4651) :874-876. |[2]Murthy JV, et al. Competitive Inhibition of High-Affinity Oryzalin Binding to Plant Tubulin by the Phosphoric Amide Herbicide Amiprophos-Methyl. Plant Physiol. 1994;105 (1) :309-320.