Griffipavixanthone
Griffipavixanthone can be extracted from Garcinia schomburgkiana. Griffipavixanthone induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. Griffipavixanthone is an anti-cancer agent. Griffipavixanthone is a weak sucrase inhibitor (IC50: 4.58 mM) [1][2][3].
Product Specifications
CAS Number
219649-95-3
Product Name Alternative
(+) -Griffipavixanthone
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/griffipavixanthone.html
Solubility
10 mM in DMSO
Smiles
OC1=C(O)C(OC2=CC(O)=CC(O)=C2C3=O)=C3C4=C1[C@@H](C5=C6C(OC7=CC(O)=CC(O)=C7C6=O)=C(C(O)=C5)O)[C@@]8([H])[C@]4([H])C=C(C)CC8(C)C
Molecular Formula
C36H28O12
Molecular Weight
652.60
References & Citations
[1]Lien Do TM, et al. Schomburgkixanthone, a novel bixanthone from the twigs of Garcinia schomburgkiana. Nat Prod Res. 2021 Nov;35 (21) :3613-3618.|[2]Shi JM, et al. Griffipavixanthone from Garcinia oblongifolia champ induces cell apoptosis in human non-small-cell lung cancer H520 cells in vitro. Molecules. 2014 Jan 27;19 (2) :1422-31.|[3]Ma Y, et al. Griffipavixanthone induces apoptosis of human breast cancer MCF-7 cells in vitro. Breast Cancer. 2019 Mar;26 (2) :190-197.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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