TLR7 agonist 1
TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM.
Product Specifications
CAS Number
2178156-33-5
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/TLR_7_agonist_1.html
Purity
98.19
Solubility
DMSO : ≥ 100 mg/mL
Smiles
NC1=NC2=C(C(C(N[C@@H](C)C3=CC=CC=C3)=O)=CC=C2)C(NCCCC)=N1
Molecular Formula
C21H25N5O
Molecular Weight
363.46
References & Citations
[1]Pieters S, et al. Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists. Bioorg Med Chem Lett. 2018 Feb 15;28 (4) :711-719.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7
Available Sizes
Frequently Asked Questions
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