ATX968
Product Specifications
UNSPSC Description
ATX968 (example 31) is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the EC50 of 0.054 μM in circBRIP1. ATX968 has antitumor activity[1].
Target Antigen
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-2.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC(NC(C2=CC(C3=NC=CC=C3C)=CS2)=O)=CC(NS(C)(=O)=O)=C1
Molecular Weight
421.92
References & Citations
[1]DANIELS Matthew H., et al. Preparation of imidazopyridines, thienopyrimidines, pyrrolopyrimidines and related heterocycles as inhibitors of RNA helicase DHX9 useful in treatment of cancers. World Intellectual Property Organization, WO2023154519 A1 2023-08-17
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156784/ATX968-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156784/ATX968-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2973395-71-8
Available Sizes
Curated Selection
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