Human CLEC-2 / CLEC1B Protein, His Tag (MALS verified)

C-type lectin-like receptor 2 (CLEC-2) is a hemITAM containing receptor that is highly expressed on platelets and regulates many of the non-classical functions of these cells, including in inflammation and infection.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 22.6 kDa. The protein migrates as 34-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q9P126-1

Expression Region

Ser 55 - Pro 229

Host

HEK293

Target

CLEC-2

Conjugation

Unconjugated

Tag

N-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.2 EU per μg

Purity

95%

Bioactivity

Immobilized Human CLEC-2, His Tag (Cat. No. CL2-H5247) at 5 μg/mL (100 μL/well) can bind Human Podoplanin, Fc Tag (Cat. No. PON-H5254) with a linear range of 0.3-20 ng/mL (QC tested).