IDOR-4
IDOR-4 is a type IV CFTR corrector. IDOR-4 restores F508del-CFTR trafficking to the cell surface[1].
Product Specifications
CAS Number
[2839901-24-3]
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/idor-4.html
Purity
98.29
Solubility
DMSO : ≥ 250 mg/mL
Smiles
CC1=C2N=CC=CC2=C3C(N[C@@H](CC(N([C@H](C(N([C@@H](C(N[C@@H](COC3=C1)CC4=CC=CC=C4)=O)CC5=NC(C(F)(F)F)=NO5)C)=O)CC(C)C)C)=O)C(NCCN6N=NC(C7CC7)=N6)=O)=O
Molecular Formula
C44H51F3N12O7
Molecular Weight
916.95
References & Citations
[1]Marchesin V, et al. A uniquely efficacious type of CFTR corrector with complementary mode of action. Sci Adv. 2024 Mar;10 (9) :eadk1814.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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