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17β-HSD7-IN-1

17β-HSD7-IN-1 (compound 4) is an inhibitor of 17β-HSD7, with inhibitory effect agasint the formation of Estradiol (IC50=63 nM) .[1].

Product Specifications

UNSPSC

12352005

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/17β-hsd7-in-1.html

Smiles

[H][C@@]12CC[C@@]3([C@]1(CC[C@]4([C@]2(CC[C@]5(NC(CC[C@]45C)=O)[H])[H])[H])C)CN(C(O3)=O)CCCCCCCCC

Molecular Formula

C29H48N2O3

Molecular Weight

472.70

References & Citations

[1]Sancéau JY, et al. Synthesis and characterization of targeted 17β-hydroxysteroid dehydrogenase type 7 inhibitors. J Steroid Biochem Mol Biol. 2024 Sep;242:106544.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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