Chikungunya virus (CHIKV) E3 & E2 & E1 Protein, His Tag (MALS verified)
Chikungunya virus (CHIKV) p62 is a structural polyprotein precursor that undergoes furin-mediated cleavage to generate the E3 and E2 glycoproteins. Co-translational association with the fusion protein E1 in the endoplasmic reticulum produces p62–E1 heterodimers that ensure proper folding and spike assembly. Following E3 removal, the mature E2–E1 complex organizes into trimeric spikes on the virion surface, mediating receptor binding and pH-triggered membrane fusion during cell entry. This coordinated processing is essential for CHIKV infectivity and immunogenicity, driving efficient virus assembly.
Product Specifications
Background
Specifications
Expression Region
Pro 266 - Arg 325 & Ser 326 - Gln 666 & Tyr 810 - Pro 1200
Target
E3 & E2 & E1
Conjugation
Unconjugated
Tag
C-10xHis
Stability
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Molecular Weight
90.6 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*1
Host or Source
HEK293
Species
Chikungunya virus (CHIKV)
Protein ID
Q1H8W5
Preservative
Trehalose
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