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Bat coronavirus Anlong103 Spike Trimer Protein (R645A, K946P, V947P), His Tag (MALS verified)

The spike protein of bat coronavirus Anlong103, a SARS-CoV-2–related sarbecovirus identified in bats from China’s Guizhou province, mediates viral entry by facilitating receptor attachment and membrane fusion. While closely related to other bat coronaviruses, Anlong103’s spike shows distinct structural features that may limit human ACE2 binding, yet retains conserved antigenic sites. These characteristics make it valuable for studying cross-species transmission potential and coronavirus evolution in wildlife reservoirs.

Product Specifications

Background

The spike protein of bat coronavirus Anlong103, a SARS-CoV-2–related sarbecovirus identified in bats from China’s Guizhou province, mediates viral entry by facilitating receptor attachment and membrane fusion. While closely related to other bat coronaviruses, Anlong103’s spike shows distinct structural features that may limit human ACE2 binding, yet retains conserved antigenic sites. These characteristics make it valuable for studying cross-species transmission potential and coronavirus evolution in wildlife reservoirs.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 133.5 kDa. The protein migrates as >160 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Asp 14 - Pro 1173

Target

Spike protein

Conjugation

Unconjugated

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

0.1 M Sodium citrate, pH5.5

Molecular Weight

133.5 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Bat coronavirus Anlong103

Protein ID

A0A1W5YKT9 (R645A, K946P, V947P)

Preservative

Trehalose

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