AICAR (phosphate)
AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy, YAP and mitophagy inhibitor[1][2].
Product Specifications
CAS Number
[681006-28-0]
Product Name Alternative
Acadesine phosphate; AICA Riboside phosphate
UNSPSC
12352005
Target
AMPK; Autophagy; Endogenous Metabolite; Mitophagy; YAP
Type
Natural Products
Related Pathways
Autophagy; Epigenetics; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/AICAR-phosphate.html
Purity
99.98
Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC(C(N)=O)=C2N)O1.O=P(O)(O)O
Molecular Formula
C9H17N4O9P
Molecular Weight
356.23
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Phase 3
Isoform
AMPK; Human Endogenous Metabolite
Citation 01
Available Sizes
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