TFF-1
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa, and functions as a gastric-specific tumor suppressor gene. Recombinant Murine TFF-1 is a 7.4 kDa monomeric protein consisting of a 66 amino acid polypeptide chain, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
Product Specifications
Synonyms
Trefoil Factor 1, pS2 protein, HP1.A, Breast Cancer Estrogen-Inducible protein (BCEI), PNR2
NCBI Gene ID
21784
UniProt
Q08423
Accession Number
NP_033388.1
Accession Number mRNA
NM_009362.2
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
QAQAQAQAQE ETCIMAPRER INCGFPGVTA QQCTERGCCF DDSVRGFPWC FHPMAIENTQ EEECPF
Assay Protocol
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Not available!
Length
66
Form
Lyophilized
Reconstitution
Water
Molecular Weight
7.4 kDa
Storage Conditions
Host or Source
E. coli
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