TECK (CCL25)
TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
CCL25; TECK; Ckb15; SCYA25
NCBI Gene ID
6370
UniProt
O15444
Accession Number
NP_005615.2
Accession Number mRNA
NM_005624
Chromosomal Location
19p13.2
Reactivity
Human
Cross Reactivity
Hamster, Mouse, Human, Monkey, Bacteria
Sequence
QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSGL
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.
Length
127
Form
Lyophilized
Molecular Weight
14.2 kDa
Host or Source
E. coli
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