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TECK (CCL25)

TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Product Specifications

Synonyms

CCL25; TECK; Ckb15; SCYA25

NCBI Gene ID

6370

UniProt

O15444

Accession Number

NP_005615.2

Accession Number mRNA

NM_005624

Chromosomal Location

19p13.2

Reactivity

Human

Cross Reactivity

Hamster, Mouse, Human, Monkey, Bacteria

Sequence

QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSGL

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.

Length

127

Form

Lyophilized

Molecular Weight

14.2 kDa

Host or Source

E. coli

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