SDF-1 alpha (CXCL12, Animal Free)
SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues.
Product Specifications
Synonyms
CXCL12; IRH; PBSF; SDF1; TLSF; SDF1A; SDF1B; TPAR1; SCYB12
NCBI Gene ID
6387
UniProt
P48061
Accession Number
NP_954637.1
Accession Number mRNA
NM_199168.3
Chromosomal Location
10q11.1
Reactivity
Human
Cross Reactivity
Human, Mouse
Sequence
KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Determined by its ability to chemoattract IL-2-activated human T cells using a concentration range of 20.0-80.0 ng/ml.
Length
68
Form
Lyophilized
Molecular Weight
8.0 kDa
Host or Source
E. coli
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
IgA Secretory Component (SC05), CF488A conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF647 conjugate, 0.1mg/mL
